Third Rock Ventures IV, L.P. Sells Shares of Tango Therapeutics, Inc.

On October 23, 2025, Third Rock Ventures IV, L.P. sold 477,401 shares of Tango Therapeutics, Inc. common stock at a weighted average price of $10.152 per share. The shares were sold in multiple transactions at prices ranging from $10.00 to $10.65. Following this transaction, Third Rock Ventures IV, L.P. still holds 13,386,574 shares of Tango Therapeutics, Inc. common stock. The transaction was reported in a Form 4 filing with the SEC. Third Rock Ventures GP IV, L.P. and TRV GP IV, LLC, the general partners of Third Rock Ventures IV, L.P., disclaim beneficial ownership of the shares except to the extent of their pecuniary interest therein.