Parkman Healthcare Partners LLC and Gregory Martinez's Ownership in Spruce Biosciences, Inc.

Parkman Healthcare Partners LLC and Gregory Martinez have reported their ownership of 1,051 shares of Common Stock in Spruce Biosciences, Inc. (SPRB) as of October 6, 2025. The shares are held indirectly through an investment in private funds, and both parties disclaim beneficial ownership except to the extent of their pecuniary interest. The filing, a Form 3, was signed on October 15, 2025, by Gregory Martinez, who serves as the Chief Investment Officer of Parkman Healthcare Partners LLC. The filing also notes that these securities were previously disclosed in a Form 3 filed on October 8, 2025.