Stock Option Grant to Director Sven Ante Lundberg

On October 23, 2025, Q32 Bio Inc. granted 53,521 stock options to its director, Sven Ante Lundberg. The options, which are exercisable at $2.80 per share, vest in full on the earlier of October 23, 2026, or the date of the company's next annual meeting of stockholders, contingent on Lundberg's continued service. The options expire on October 22, 2035. This transaction is reported under Form 4, indicating a change in beneficial ownership.