RA Capital Management, L.P. and Affiliates File Schedule 13G for Palisade Bio, Inc.

RA Capital Management, L.P., along with Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P., filed a Schedule 13G with the SEC on October 9, 2025, disclosing their beneficial ownership of Palisade Bio, Inc. common stock. The filing indicates that each reporting person beneficially owns 9.9% of the company's common stock, totaling 9,935,761 shares. The ownership includes shares held directly by RA Capital Healthcare Fund, L.P., and shares issuable upon the exercise of pre-funded warrants. The pre-funded warrants contain a beneficial ownership blocker that limits the exercise to prevent ownership from exceeding 9.99% of the outstanding common stock. RA Capital Management, L.P. serves as the investment adviser for RA Capital Healthcare Fund, L.P., and has been delegated the sole power to vote and dispose of the securities held by the fund. Peter Kolchinsky and Rajeev Shah, as managers of RA Capital Management, L.P., may also be deemed beneficial owners of the securities. The filing includes a joint filing agreement among the reporting persons.