D. E. Shaw & Co. Reports 5.1% Ownership in Keros Therapeutics

D. E. Shaw & Co., L.P., D. E. Shaw & Co., L.L.C., and David E. Shaw have reported a 5.1% ownership in Keros Therapeutics, Inc. as of October 20, 2025. The shares are held through various entities managed by D. E. Shaw & Co., L.P. and D. E. Shaw & Co., L.L.C. David E. Shaw, as the President and sole shareholder of the general partner and managing member entities, may be deemed to have shared voting and dispositive power over the shares. The filing is made pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934. The reporting persons certify that the shares were not acquired for the purpose of influencing the control of the issuer.