Bryan Supran's Ownership Disclosure for Alnylam Pharmaceuticals, Inc.

The filing discloses the ownership details of Bryan Supran, Executive Vice President, Chief Legal Officer, and Secretary of Alnylam Pharmaceuticals, Inc. The document, filed under Form 3, indicates that Bryan Supran does not own any securities of the company as of the period of report dated September 15, 2025. The filing includes the reporting owner's address in Cambridge, MA, and is signed by Brett Budzinski as Attorney-in-Fact for Bryan Supran. The document also lists an exhibit, specifically Exhibit 24 - Power of Attorney.