Amendment to Schedule 13G Filing for Alpha Cognition Inc.

Opaleye Management Inc., Opaleye, L.P., and James Silverman have jointly filed an amendment to their Schedule 13G, reporting increased beneficial ownership of Alpha Cognition Inc. common stock. As of March 4, 2026, their combined ownership stands at 11.00%, representing 2,388,638 shares. This filing, designated as amendment number 3, indicates a shift from a previous ownership of 10.09%. The filing clarifies that while Opaleye, L.P. directly holds a portion of these shares, Opaleye Management Inc. acts as the investment adviser, and James Silverman exercises control over the Adviser. The joint filing agreement ensures coordinated reporting of their holdings.