The Analysis of Opaleye Management Inc.'s Holdings


Currently, Opaleye Management Inc. holds 54 types of securities in its portfolio with a total value $764.1M. In the most recent quarter, they have increased their positions in HROW (+3.9M shares, valued at $191.3M), LQDA (+2.4M shares, valued at $85.0M), ETON (+2.9M shares, valued at $48.4M); initiated new positions in HROW (+3.9M shares, valued at $191.3M), LQDA (+2.4M shares, valued at $85.0M), ETON (+2.9M shares, valued at $48.4M).


Top Holding Treemap

Stock Holdings
TickerCompany NameSharesShares â–ŗ%Event DateReport DateHistory
HROW HARROW HEALTH INC3.9M sharesnew addition2025-12-312026-02-17history
LQDA LIQUIDIA CORPORATION2.4M sharesnew addition2025-12-312026-02-17history
ETON ETON PHARMACEUTICALS INC2.9M sharesnew addition2025-12-312026-02-17history
RYTM RHYTHM PHARMACEUTICALS INC330.0K sharesnew addition2025-12-312026-02-17history
APGE APOGEE THERAPEUTICS INC388.3K sharesnew addition2025-12-312026-02-17history
SNWV SANUWAVE HEALTH INC981.3K sharesnew addition2025-12-312026-02-17history
STOK STOKE THERAPEUTICS INC695.0K sharesnew addition2025-12-312026-02-17history
OCUL OCULAR THERAPEUTIX INC1.6M sharesnew addition2025-12-312026-02-17history
Sponsored
SLGL SOL GEL TECHNOLOGIES453.7K sharesnew addition2025-12-312026-02-17history
CGON CG ONCOLOGY INC410.0K sharesnew addition2025-12-312026-02-17history
TGTX TG THERAPEUTICS INC535.0K sharesnew addition2025-12-312026-02-17history
IRON DISC MEDICINE INC200.0K sharesnew addition2025-12-312026-02-17history
RZLT REZOLUTE INC6.3M sharesnew addition2025-12-312026-02-17history
ACOG ALPHA COGNITION INC2.4M shares8.89%2026-03-022026-03-04history
CRESCENT BIOPHARMA INC CRESCENT BIOPHARMA INC1.2M sharesnew addition2025-12-312026-02-17history
ALKS ALKERMES PLC490.0K sharesnew addition2025-12-312026-02-17history
Sponsored
ANNX ANNEXON INC2.6M sharesnew addition2025-12-312026-02-17history
EWTX EDGEWISE THERAPEUTICS INC500.0K sharesnew addition2025-12-312026-02-17history
CDXS CODEXIS INC6.8M sharesnew addition2025-12-312026-02-17history
PTGX PROTAGONIST THERAPEUTICS INC105.0K sharesnew addition2025-12-312026-02-17history
GOSS GOSSAMER BIO INC2.7M sharesnew addition2025-12-312026-02-17history
MBX MBX BIOSCIENCES INC260.0K sharesnew addition2025-12-312026-02-17history
RVMD REVOLUTION MEDICINES INC100.0K sharesnew addition2025-12-312026-02-17history
XOMA XOMA CORP DEL292.6K sharesnew addition2025-12-312026-02-17history
Sponsored
DERM JOURNEY MEDICAL CORP975.0K sharesnew addition2025-12-312026-02-17history
KPTI KARYOPHARM THERAPEUTICS INC930.0K sharesnew addition2025-12-312026-02-17history
JBIO JADE BIOSCIENCES INC427.6K sharesnew addition2025-12-312026-02-17history
URGN UROGEN PHARMA LTD268.4K sharesnew addition2025-12-312026-02-17history
QTTB Q32 BIO INC1.3M shares488.77%2026-02-192026-02-20history
ALMS ALUMIS INC535.0K sharesnew addition2025-12-312026-02-17history
CATX PERSPECTIVE THERAPEUTICS INC1.2M sharesnew addition2025-12-312026-02-17history
VYGR VOYAGER THERAPEUTICS INC1.2M sharesnew addition2025-12-312026-02-17history
Sponsored
RLMD RELMADA THERAPEUTICS INC935.0K sharesnew addition2025-12-312026-02-17history
TECX TECTONIC THERAPEUTICS INC214.7K sharesnew addition2025-12-312026-02-17history
PLX PROTALIX BIOTHERAPEUTICS INC2.5M sharesnew addition2025-12-312026-02-17history
TRVI TREVI THERAPEUTICS INC345.1K sharesnew addition2025-12-312026-02-17history
FORTRESS BIOTECH INC FORTRESS BIOTECH INC1.1M sharesnew addition2025-12-312026-02-17history
RCKT ROCKET PHARMACEUTICALS INC955.0K sharesnew addition2025-12-312026-02-17history
MGTX MEIRAGTX HOLDINGS PLC390.8K sharesnew addition2025-12-312026-02-17history
RIGL RIGEL PHARMACEUTICALS INC70.0K sharesnew addition2025-12-312026-02-17history
Sponsored
ZYMEWORKS INC ZYMEWORKS INC108.9K sharesnew addition2025-12-312026-02-17history
ASRT ASSERTIO HOLDINGS INC285.0K sharesnew addition2025-12-312026-02-17history
VTYX VENTYX BIOSCIENCES INC251.9K sharesnew addition2025-12-312026-02-17history
IRD OPUS GENETICS INC1.1M sharesnew addition2025-12-312026-02-17history
SUTRO BIOPHARMA INC SUTRO BIOPHARMA INC190.7K sharesnew addition2025-12-312026-02-17history
CABA CABALETTA BIO INC900.0K sharesnew addition2025-12-312026-02-17history
ZNTL ZENTALIS PHARMACEUTICALS INC1.4M sharesnew addition2025-12-312026-02-17history
GBIO GENERATION BIO CO310.0K sharesnew addition2025-12-312026-02-17history
Sponsored
BBIO BRIDGEBIO PHARMA INC18.3K sharesnew addition2025-12-312026-02-17history
ENTA ENANTA PHARMACEUTICALS INC75.0K sharesnew addition2025-12-312026-02-17history
AVIR ATEA PHARMACEUTICALS INC179.8K sharesnew addition2025-12-312026-02-17history
SLN SILENCE THERAPEUTICS PLC78.9K sharesnew addition2025-12-312026-02-17history
RAPT THERAPEUTICS INC RAPT THERAPEUTICS INC150.0K sharesnew addition2025-12-312026-02-17history
ADGM ADAGIO MED HLDGS INC110.6K sharesnew addition2025-12-312026-02-17history

Call Option Holdings
No call option holdings data available

Put Option Holdings
No put option holdings data available