Top Biotech Institutional P&L

Estimated portfolio P&L ranking for biotech-focused institutions, based on reported 13F stock holdings. Due to the inherent delay in 13F filings and various factors such as stock split adjustments, this ranking is a best-effort estimate and may contain inaccuracies.

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#Institution1M P&L3M P&LHY P&L

1FARALLON CAPITAL MANAGEMENT LLC+1.37%+21.61%+35.21%

2BAKER BROS. ADVISORS LP+3.12%+28.65%+25.43%

3Avoro Capital Advisors LLC+4.27%+17.55%+18.80%

4RA CAPITAL MANAGEMENT, L.P.+1.01%+25.03%+12.94%

5RTW INVESTMENTS, LP+1.80%+25.87%+26.72%

6DEERFIELD MANAGEMENT COMPANY, L.P.-0.45%+9.17%+9.14%

7PERCEPTIVE ADVISORS LLC+5.29%+30.43%+31.30%

8Paradigm Biocapital Advisors LP+1.49%+32.11%+35.27%

9Deep Track Capital, LP-0.09%+22.10%+22.52%

10ORBIMED ADVISORS LLC+1.93%+19.20%+17.27%

11Bellevue Group AG+4.13%+23.11%+16.90%

12Frazier Life Sciences Management, L.P.-1.60%+18.21%+13.71%

13Darwin Global Management, Ltd.-0.82%+31.61%+1.60%

14SUVRETTA CAPITAL MANAGEMENT, LLC-0.76%+5.00%+4.52%

15Vestal Point Capital, LP+1.25%+24.99%+25.69%

16Siren, L.L.C.-1.38%+26.98%+25.32%

17TCG Crossover Management, LLC-3.36%+27.85%+23.27%

18BVF INC/IL+3.65%+28.65%+25.26%

19BRAIDWELL LP+6.00%+38.11%+48.61%

20Venrock Adviser, LLC-3.38%+41.62%+47.02%

21GILEAD SCIENCES, INC.+7.00%+29.84%+25.91%

22Soleus Capital Management, L.P.+5.41%+17.39%+26.01%

23DeepCurrents Investment Group LLC+1.94%+5.81%-13.30%

24EcoR1 Capital, LLC+2.88%+38.05%+35.97%

25TANG CAPITAL MANAGEMENT LLC+7.57%+14.92%+17.94%

1FARALLON CAPITAL MANAGEMENT LLC

1M P&L+1.37%

3M P&L+21.61%

HY P&L+35.21%

2BAKER BROS. ADVISORS LP

1M P&L+3.12%

3M P&L+28.65%

HY P&L+25.43%

3Avoro Capital Advisors LLC

1M P&L+4.27%

3M P&L+17.55%

HY P&L+18.80%

4RA CAPITAL MANAGEMENT, L.P.

1M P&L+1.01%

3M P&L+25.03%

HY P&L+12.94%

5RTW INVESTMENTS, LP

1M P&L+1.80%

3M P&L+25.87%

HY P&L+26.72%

6DEERFIELD MANAGEMENT COMPANY, L.P.

1M P&L-0.45%

3M P&L+9.17%

HY P&L+9.14%

7PERCEPTIVE ADVISORS LLC

1M P&L+5.29%

3M P&L+30.43%

HY P&L+31.30%

8Paradigm Biocapital Advisors LP

1M P&L+1.49%

3M P&L+32.11%

HY P&L+35.27%

9Deep Track Capital, LP

1M P&L-0.09%

3M P&L+22.10%

HY P&L+22.52%

10ORBIMED ADVISORS LLC

1M P&L+1.93%

3M P&L+19.20%

HY P&L+17.27%

11Bellevue Group AG

1M P&L+4.13%

3M P&L+23.11%

HY P&L+16.90%

12Frazier Life Sciences Management, L.P.

1M P&L-1.60%

3M P&L+18.21%

HY P&L+13.71%

13Darwin Global Management, Ltd.

1M P&L-0.82%

3M P&L+31.61%

HY P&L+1.60%

14SUVRETTA CAPITAL MANAGEMENT, LLC

1M P&L-0.76%

3M P&L+5.00%

HY P&L+4.52%

15Vestal Point Capital, LP

1M P&L+1.25%

3M P&L+24.99%

HY P&L+25.69%

16Siren, L.L.C.

1M P&L-1.38%

3M P&L+26.98%

HY P&L+25.32%

17TCG Crossover Management, LLC

1M P&L-3.36%

3M P&L+27.85%

HY P&L+23.27%

1M P&L+3.65%

3M P&L+28.65%

HY P&L+25.26%

1M P&L+6.00%

3M P&L+38.11%

HY P&L+48.61%

20Venrock Adviser, LLC

1M P&L-3.38%

3M P&L+41.62%

HY P&L+47.02%

21GILEAD SCIENCES, INC.

1M P&L+7.00%

3M P&L+29.84%

HY P&L+25.91%

22Soleus Capital Management, L.P.

1M P&L+5.41%

3M P&L+17.39%

HY P&L+26.01%

23DeepCurrents Investment Group LLC

1M P&L+1.94%

3M P&L+5.81%

HY P&L-13.30%

24EcoR1 Capital, LLC

1M P&L+2.88%

3M P&L+38.05%

HY P&L+35.97%

25TANG CAPITAL MANAGEMENT LLC

1M P&L+7.57%

3M P&L+14.92%

HY P&L+17.94%