Top Biotech Institutional P&L

Estimated portfolio P&L ranking for biotech-focused institutions, based on reported 13F stock holdings. Due to the inherent delay in 13F filings and various factors such as stock split adjustments, this ranking is a best-effort estimate and may contain inaccuracies.

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#Institution1M P&L3M P&LHY P&L

1BAKER BROS. ADVISORS LP+14.56%+5.43%+7.61%

2Avoro Capital Advisors LLC+6.61%+7.23%+16.61%

3RTW INVESTMENTS, LP+11.42%+10.00%+18.55%

4RA CAPITAL MANAGEMENT, L.P.+12.86%+3.77%+14.59%

5DEERFIELD MANAGEMENT COMPANY, L.P.+5.55%+8.21%+15.46%

6PERCEPTIVE ADVISORS LLC+10.57%+9.94%+30.89%

7Paradigm Biocapital Advisors LP+12.17%+10.23%+22.26%

8ORBIMED ADVISORS LLC+14.36%+9.91%+12.00%

9Deep Track Capital, LP+9.79%+16.35%+14.17%

10Bellevue Group AG+10.31%+7.43%+4.37%

11Frazier Life Sciences Management, L.P.+15.50%+12.46%+22.61%

12Darwin Global Management, Ltd.+14.29%-12.42%-15.33%

13SUVRETTA CAPITAL MANAGEMENT, LLC+4.78%+5.06%+9.99%

14Siren, L.L.C.+13.89%+11.78%+26.50%

15Vestal Point Capital, LP+13.90%+10.20%+19.20%

16TCG Crossover Management, LLC+18.63%+8.27%+31.88%

17BVF INC/IL+15.35%+14.42%+21.00%

18BRAIDWELL LP+18.14%+29.36%+16.49%

19Fairmount Funds Management LLC+20.21%+17.65%+84.21%

20Venrock Adviser, LLC+27.85%+20.37%+59.27%

21Soleus Capital Management, L.P.+7.70%+15.45%+16.93%

22DeepCurrents Investment Group LLC+3.99%-15.95%-64.91%

23EcoR1 Capital, LLC+22.05%+18.30%+39.85%

24GILEAD SCIENCES, INC.+11.66%+10.88%+23.61%

25Cormorant Asset Management, LP+17.52%+5.70%+22.17%

1BAKER BROS. ADVISORS LP

1M P&L+14.56%

3M P&L+5.43%

HY P&L+7.61%

2Avoro Capital Advisors LLC

1M P&L+6.61%

3M P&L+7.23%

HY P&L+16.61%

3RTW INVESTMENTS, LP

1M P&L+11.42%

3M P&L+10.00%

HY P&L+18.55%

4RA CAPITAL MANAGEMENT, L.P.

1M P&L+12.86%

3M P&L+3.77%

HY P&L+14.59%

5DEERFIELD MANAGEMENT COMPANY, L.P.

1M P&L+5.55%

3M P&L+8.21%

HY P&L+15.46%

6PERCEPTIVE ADVISORS LLC

1M P&L+10.57%

3M P&L+9.94%

HY P&L+30.89%

7Paradigm Biocapital Advisors LP

1M P&L+12.17%

3M P&L+10.23%

HY P&L+22.26%

8ORBIMED ADVISORS LLC

1M P&L+14.36%

3M P&L+9.91%

HY P&L+12.00%

9Deep Track Capital, LP

1M P&L+9.79%

3M P&L+16.35%

HY P&L+14.17%

10Bellevue Group AG

1M P&L+10.31%

3M P&L+7.43%

HY P&L+4.37%

11Frazier Life Sciences Management, L.P.

1M P&L+15.50%

3M P&L+12.46%

HY P&L+22.61%

12Darwin Global Management, Ltd.

1M P&L+14.29%

3M P&L-12.42%

HY P&L-15.33%

13SUVRETTA CAPITAL MANAGEMENT, LLC

1M P&L+4.78%

3M P&L+5.06%

HY P&L+9.99%

14Siren, L.L.C.

1M P&L+13.89%

3M P&L+11.78%

HY P&L+26.50%

15Vestal Point Capital, LP

1M P&L+13.90%

3M P&L+10.20%

HY P&L+19.20%

16TCG Crossover Management, LLC

1M P&L+18.63%

3M P&L+8.27%

HY P&L+31.88%

1M P&L+15.35%

3M P&L+14.42%

HY P&L+21.00%

1M P&L+18.14%

3M P&L+29.36%

HY P&L+16.49%

19Fairmount Funds Management LLC

1M P&L+20.21%

3M P&L+17.65%

HY P&L+84.21%

20Venrock Adviser, LLC

1M P&L+27.85%

3M P&L+20.37%

HY P&L+59.27%

21Soleus Capital Management, L.P.

1M P&L+7.70%

3M P&L+15.45%

HY P&L+16.93%

22DeepCurrents Investment Group LLC

1M P&L+3.99%

3M P&L-15.95%

HY P&L-64.91%

23EcoR1 Capital, LLC

1M P&L+22.05%

3M P&L+18.30%

HY P&L+39.85%

24GILEAD SCIENCES, INC.

1M P&L+11.66%

3M P&L+10.88%

HY P&L+23.61%

25Cormorant Asset Management, LP

1M P&L+17.52%

3M P&L+5.70%

HY P&L+22.17%