Form 4 Filing for Sionna Therapeutics, Inc. - Thompson Peter A.

Peter A. Thompson, a director at Sionna Therapeutics, Inc., was granted 17,340 non-qualified stock options on June 17, 2026. These options, exercisable at $36.73 per share, will vest in full on the earlier of June 17, 2027, or the next annual meeting, contingent upon continued service. The securities are subject to a transfer obligation to OrbiMed entities as per an agreement with OrbiMed Advisors LLC and OrbiMed Capital GP VIII LLC. Following the transaction, Thompson holds 17,340 shares underlying these options.