Form 4 Filing for Otello Stampacchia

This filing details a Form 4 submission by Otello Stampacchia, a director at ImageneBio, Inc. The transaction, dated June 16, 2026, involves the acquisition of 15,600 stock options with a strike price of $5.45. These options are exercisable upon specific vesting conditions, including the first anniversary of the grant date, the issuer's next annual meeting, or a change of control. The options are set to expire on June 16, 2036. Following this transaction, Stampacchia holds 15,600 shares of common stock underlying these options. The filing was signed by Kristin Yarema as attorney-in-fact on June 18, 2026.