Initial Statement of Beneficial Ownership

This filing details the initial statement of beneficial ownership for James Huang, a director at CASI Pharmaceuticals, Inc. As of March 18, 2026, Huang directly holds 10000 stock options exercisable at $1.69, expiring on October 1, 2035, and another 10000 stock options exercisable at $2.69, expiring on May 1, 2033. Additionally, he holds 101,571 stock options exercisable at $1.93, expiring on March 20, 2026. Huang may also be deemed to share beneficial ownership of 4,529,956 Ordinary Shares held by Panacea Venture Healthcare Fund II, L.P., although he disclaims such beneficial ownership. The stock options mentioned are fully vested.