Power of Attorney for Andrea Pfeifer

This filing details a Power of Attorney granted by Andrea Pfeifer, CEO of AC Immune SA, to Christopher Roberts, Tim Kay, and Matthias Maurer. The attorneys-in-fact are authorized to manage SEC filings, including Forms 3, 4, and 5, and to execute and file Form 144 for stock sales. The document also outlines the authority to obtain and maintain EDGAR system credentials and to perform any necessary actions related to these filings. Andrea Pfeifer holds directly 3,840,288 common shares and indirectly 14,000 common shares. She also holds various share options with exercise prices ranging from $2.03 to $9.53, and expiration dates extending to 2032.