Form 4 Filing for June Carl Howard at AC Immune SA

On June 11, 2026, June Carl Howard, a director at AC Immune SA, acquired 16,568 restricted share units under the company's 2016 Stock Option and Incentive Plan (SOIP). The value of these units was $0.00 per share, as noted in footnote F1. Following this transaction, Howard holds a total of 67,556 common shares, which includes the 66,556 common shares underlying outstanding restricted share units, as indicated in footnote F2. Additionally, on the same date, Howard received options to purchase 38,889 common shares under the SOIP. These options have an exercise price of $2.62 and are set to fully vest on June 10, 2027, with an expiration date of June 10, 2036. The shares acquired through these options are considered directly owned.