The Analysis of SPHERA FUNDS MANAGEMENT LTD.'s Holdings

Currently, SPHERA FUNDS MANAGEMENT LTD. holds 94 types of securities in its portfolio with a total value $478.5M. In the most recent quarter, they have increased their positions in TEVA (+1.1M shares, valued at $35.1M), BIIB (+94.7K shares, valued at $16.7M), MLYS (+449.0K shares, valued at $16.3M); initiated new positions in TEVA (+1.1M shares, valued at $35.1M), BIIB (+94.7K shares, valued at $16.7M), MLYS (+449.0K shares, valued at $16.3M).

Top Holding Treemap

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

TEVA TEVA PHARMACEUTICAL INDS LTD1.1M sharesnew addition2025-12-312026-02-17

BIIB BIOGEN INC94.7K sharesnew addition2025-12-312026-02-17

MLYS MINERALYS THERAPEUTICS INC449.0K sharesnew addition2025-12-312026-02-17

SNDX SYNDAX PHARMACEUTICALS INC762.6K sharesnew addition2025-12-312026-02-17

NVMI NOVA LTD47.8K sharesnew addition2025-12-312026-02-17

TSEM TOWER SEMICONDUCTOR LTD122.5K sharesnew addition2025-12-312026-02-17

COGT COGENT BIOSCIENCES INC378.5K sharesnew addition2025-12-312026-02-17

AZN ASTRAZENECA PLC135.1K sharesnew addition2025-12-312026-02-17

Sponsored

SNY SANOFI SA239.5K sharesnew addition2025-12-312026-02-17

LLY ELI LILLY & CO9.0K sharesnew addition2025-12-312026-02-17

FOLD AMICUS THERAPEUTICS INC658.4K sharesnew addition2025-12-312026-02-17

IMTX IMMATICS N.V861.1K sharesnew addition2025-12-312026-02-17

BMRN BIOMARIN PHARMACEUTICAL INC147.0K sharesnew addition2025-12-312026-02-17

BBIO BRIDGEBIO PHARMA INC107.7K sharesnew addition2025-12-312026-02-17

ORIC ORIC PHARMACEUTICALS INC1.0M sharesnew addition2025-12-312026-02-17

DYN DYNE THERAPEUTICS INC392.9K sharesnew addition2025-12-312026-02-17

Sponsored

TRVI TREVI THERAPEUTICS INC598.5K sharesnew addition2025-12-312026-02-17

JNJ JOHNSON & JOHNSON35.8K sharesnew addition2025-12-312026-02-17

SVRA SAVARA INC1.2M sharesnew addition2025-12-312026-02-17

SRRK SCHOLAR ROCK HLDG CORP158.3K sharesnew addition2025-12-312026-02-17

WVE WAVE LIFE SCIENCES LTD408.2K sharesnew addition2025-12-312026-02-17

RARE ULTRAGENYX PHARMACEUTICAL IN300.6K sharesnew addition2025-12-312026-02-17

CYBN CYBIN INC825.6K sharesnew addition2025-12-312026-02-17

ANNX ANNEXON INC1.3M sharesnew addition2025-12-312026-02-17

Sponsored

BCRX BIOCRYST PHARMACEUTICALS INC837.9K sharesnew addition2025-12-312026-02-17

CLDX CELLDEX THERAPEUTICS INC NEW239.8K sharesnew addition2025-12-312026-02-17

SOLENO THERAPEUTICS INC SOLENO THERAPEUTICS INC136.3K sharesnew addition2025-12-312026-02-17

APLS APELLIS PHARMACEUTICALS INC251.0K sharesnew addition2025-12-312026-02-17

GSK PLC GSK PLC122.0K sharesnew addition2025-12-312026-02-17

ENPH ENPHASE ENERGY INC186.5K sharesnew addition2025-12-312026-02-17

NVO NOVO-NORDISK A S115.7K sharesnew addition2025-12-312026-02-17

CYTK CYTOKINETICS INC91.7K sharesnew addition2025-12-312026-02-17

Sponsored

ABBV ABBVIE INC25.3K sharesnew addition2025-12-312026-02-17

SEDG SOLAREDGE TECHNOLOGIES INC196.5K sharesnew addition2025-12-312026-02-17

ACAD ACADIA PHARMACEUTICALS INC212.2K sharesnew addition2025-12-312026-02-17

VOR VOR BIOPHARMA INC410.4K sharesnew addition2025-12-312026-02-17

MERCK & CO INC MERCK & CO INC48.6K sharesnew addition2025-12-312026-02-17

NVS NOVARTIS AG37.0K sharesnew addition2025-12-312026-02-17

FORTE BIOSCIENCES INC FORTE BIOSCIENCES INC185.9K sharesnew addition2025-12-312026-02-17

KOD KODIAK SCIENCES INC175.5K sharesnew addition2025-12-312026-02-17

Sponsored

TNGX TANGO THERAPEUTICS INC544.6K sharesnew addition2025-12-312026-02-17

SOLAREDGE TECHNOLOGIES INC SOLAREDGE TECHNOLOGIES INC4.0M sharesnew addition2025-12-312026-02-17

ATXS ASTRIA THERAPEUTICS INC355.7K sharesnew addition2025-12-312026-02-17

MEDIWOUND LTD MEDIWOUND LTD230.3K sharesnew addition2025-12-312026-02-17

CAMT CAMTEK LTD39.5K sharesnew addition2025-12-312026-02-17

RVMD REVOLUTION MEDICINES INC52.5K sharesnew addition2025-12-312026-02-17

AMD ADVANCED MICRO DEVICES INC18.0K sharesnew addition2025-12-312026-02-17

CLYM CLIMB BIO INC932.2K sharesnew addition2025-12-312026-02-17

Sponsored

ACOG ALPHA COGNITION INC567.6K sharesnew addition2025-12-312026-02-17

ELVN ENLIVEN THERAPEUTICS INC226.8K sharesnew addition2025-12-312026-02-17

TARA PROTARA THERAPEUTICS INC650.0K sharesnew addition2025-12-312026-02-17

BROADCOM INC BROADCOM INC9.8K sharesnew addition2025-12-312026-02-17

ELDN ELEDON PHARMACEUTICALS INC2.1M sharesnew addition2025-12-312026-02-17

BIOA BIOAGE LABS INC243.0K sharesnew addition2025-12-312026-02-17

CRVS CORVUS PHARMACEUTICALS INC407.7K sharesnew addition2025-12-312026-02-17

ESLT ELBIT SYS LTD5.3K sharesnew addition2025-12-312026-02-17

Sponsored

KURA KURA ONCOLOGY INC295.5K sharesnew addition2025-12-312026-02-17

MAZE MAZE THERAPEUTICS INC71.8K sharesnew addition2025-12-312026-02-17

ZIM ZIM INTEGRATED SHIPPING SERV136.0K sharesnew addition2025-12-312026-02-17

GPCR STRUCTURE THERAPEUTICS INC41.0K sharesnew addition2025-12-312026-02-17

EVOMMUNE INC EVOMMUNE INC166.1K sharesnew addition2025-12-312026-02-17

VERASTEM INC VERASTEM INC343.7K sharesnew addition2025-12-312026-02-17

AMGN AMGEN INC7.5K sharesnew addition2025-12-312026-02-17

NRIX NURIX THERAPEUTICS INC124.0K sharesnew addition2025-12-312026-02-17

Sponsored

ASND ASCENDIS PHARMA A/S11.0K sharesnew addition2025-12-312026-02-17

TENAX THERAPEUTICS INC TENAX THERAPEUTICS INC190.1K sharesnew addition2025-12-312026-02-17

JANX JANUX THERAPEUTICS INC157.8K sharesnew addition2025-12-312026-02-17

PFE PFIZER INC86.0K sharesnew addition2025-12-312026-02-17

TSHA TAYSHA GENE THERAPIES INC368.1K sharesnew addition2025-12-312026-02-17

CTNM CONTINEUM THERAPEUTICS INC173.5K sharesnew addition2025-12-312026-02-17

MDGL MADRIGAL PHARMACEUTICALS INC3.3K sharesnew addition2025-12-312026-02-17

PHVS PHARVARIS N V64.0K sharesnew addition2025-12-312026-02-17

Sponsored

VRNS VARONIS SYS INC52.5K sharesnew addition2025-12-312026-02-17

PRECISION BIOSCIENCES INC PRECISION BIOSCIENCES INC396.1K sharesnew addition2025-12-312026-02-17

VTYX VENTYX BIOSCIENCES INC180.1K sharesnew addition2025-12-312026-02-17

IBIT ISHARES BITCOIN TRUST ETF30.1K sharesnew addition2025-12-312026-02-17

DAWN DAY ONE BIOPHARMACEUTICALS I145.4K sharesnew addition2025-12-312026-02-17

VYGR VOYAGER THERAPEUTICS INC339.8K sharesnew addition2025-12-312026-02-17

TRDA ENTRADA THERAPEUTICS INC110.9K sharesnew addition2025-12-312026-02-17

TNYA TENAYA THERAPEUTICS INC1.5M sharesnew addition2025-12-312026-02-17

Sponsored

CATX PERSPECTIVE THERAPEUTICS INC350.0K sharesnew addition2025-12-312026-02-17

BMY BRISTOL-MYERS SQUIBB CO17.5K sharesnew addition2025-12-312026-02-17

JASPER THERAPEUTICS INC JASPER THERAPEUTICS INC485.4K sharesnew addition2025-12-312026-02-17

PEPG PEPGEN INC121.5K sharesnew addition2025-12-312026-02-17

STTK SHATTUCK LABS INC195.2K sharesnew addition2025-12-312026-02-17

PALISADE BIO INC PALISADE BIO INC184.1K sharesnew addition2025-12-312026-02-17

HOWL WEREWOLF THERAPEUTICS INC626.8K sharesnew addition2025-12-312026-02-17

SKYE BIOSCIENCE INC SKYE BIOSCIENCE INC478.9K sharesnew addition2025-12-312026-02-17

Sponsored

PRLD PRELUDE THERAPEUTICS INC122.8K sharesnew addition2025-12-312026-02-17

APREA THERAPEUTICS INC APREA THERAPEUTICS INC270.0K sharesnew addition2025-12-312026-02-17

ONKURE THERAPEUTICS INC ONKURE THERAPEUTICS INC60.5K sharesnew addition2025-12-312026-02-17

MREO MEREO BIOPHARMA GROUP PLC255.4K sharesnew addition2025-12-312026-02-17

PROMIS NEUROSCIENCES INC PROMIS NEUROSCIENCES INC11.8K sharesnew addition2025-12-312026-02-17

APLT APPLIED THERAPEUTICS INC50.0K sharesnew addition2025-12-312026-02-17

Call Option Holdings

PRAXIS PRECISION MEDICINES I Call CallPRAXIS PRECISION MEDICINES I40.0K sharesnew addition2025-12-312026-02-17

RARE Call CallULTRAGENYX PHARMACEUTICAL IN350.0K sharesnew addition2025-12-312026-02-17

NICE Call CallNICE LTD55.7K sharesnew addition2025-12-312026-02-17

TLT Call CallISHARES TR47.0K sharesnew addition2025-12-312026-02-17

Put Option Holdings

XBI Put PutSPDR SERIES TRUST70.0K sharesnew addition2025-12-312026-02-17