Sponsored

The Analysis of RA CAPITAL MANAGEMENT, L.P.'s Holdings & P&L

Currently, RA CAPITAL MANAGEMENT, L.P. holds 82 types of securities in its portfolio with a total value $9.7B. In the most recent quarter, they have increased their positions in ASND (+10.3M shares, valued at $2.2B), RNA (+8.6M shares, valued at $623.3M), RYTM (+6.7M shares, valued at $587.5M); decreased their positions in N/A (-3.4M shares, valued at $743.4M), IRON (-252.8K shares, valued at $20.1M); initiated new positions in ASND (+10.3M shares, valued at $2.2B), RNA (+8.6M shares, valued at $623.3M), RYTM (+6.7M shares, valued at $587.5M); completely sold out of N/A (previously valued at $743.4M).

1M P&L

-37.1M-0.42%

3M P&L

-375.5M-4.12%

HY P&L

+164.1M+1.91%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology9.1B

97.7%

2Drug Manufacturers - Specialty & Generic123.5M

1.3%

3Diagnostics & Research44.2M

0.5%

Top Industries by Stock Count

1Biotechnology57 stocks

83.8%

2Health Information Services3 stocks

4.4%

3Medical Devices2 stocks

2.9%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

ASND ASCENDIS PHARMA A/S - ADR10.3M sharesnew addition2025-12-312026-02-17

RNA AVIDITY BIOSCIENCES INC8.6M sharesnew addition2025-12-312026-02-17

RYTM 6.7M sharesnew addition2025-12-312026-02-17

PCVX VAXCYTE INC10.7M sharesnew addition2025-12-312026-02-17

TYRA TYRA BIOSCIENCES INC12.3M shares0.56%2026-03-042026-03-06

SION SIONNA THERAPEUTICS INC9.9M sharesnew addition2025-12-312026-02-17

NAMS NEWAMSTERDAM PHARMA CO NV9.6M sharesnew addition2025-12-312026-02-17

WVE WAVE LIFE SCIENCES LTD18.2M sharesnew addition2025-12-312026-02-17

Sponsored

MLYS MINERALYS THERAPEUTICS INC7.3M sharesnew addition2025-12-312026-02-17

EWTX EDGEWISE THERAPEUTICS INC10.4M sharesnew addition2025-12-312026-02-17

DNTH 2.6M sharesnew addition2025-12-312026-02-17

ACET 22.6M shares74.09%2026-04-272026-04-29

SEPN SEPTERNA INC7.0M sharesnew addition2025-12-312026-02-17

NUVL NUVALENT INC-A1.9M sharesnew addition2025-12-312026-02-17

IRON DISC MEDICINE INC2.0M shares-11.34%2025-12-312026-02-17

JANX JANUX THERAPEUTICS INC11.2M sharesnew addition2025-12-312026-02-17

Sponsored

ACLX 1.3M sharesnew addition2025-12-312026-02-17

PEPG PEPGEN INC20.1M sharesnew addition2025-12-312026-02-17

TSHA TAYSHA GENE THERAPIES INC23.6M sharesnew addition2025-12-312026-02-17

SPRY ARS PHARMACEUTICALS INC10.9M sharesnew addition2025-12-312026-02-17

BCRX BIOCRYST PHARMACEUTICALS INC15.8M sharesnew addition2025-12-312026-02-17

BCAX BICARA THERAPEUTICS INC7.3M shares4.65%2026-02-262026-03-02

PRAXIS PRECISION MEDICINES I PRAXIS PRECISION MEDICINES I373.8K sharesnew addition2025-12-312026-02-17

GHRS GH RESEARCH PLC7.7M sharesnew addition2025-12-312026-02-17

Sponsored

GERN GERON CORP63.8M sharesnew addition2025-12-312026-02-17

EVOMMUNE INC EVOMMUNE INC3.5M shares1.04%2026-02-122026-02-17

CLYM CLIMB BIO INC11.3M sharesnew addition2025-12-312026-02-17

SOLID BIOSCIENCES INC SOLID BIOSCIENCES INC9.7M shares66.29%2026-03-062026-03-10

VOR VOR BIOPHARMA INC5.4M sharesnew addition2025-12-312026-02-17

BLTE BELITE BIO INC - ADR432.5K sharesnew addition2025-12-312026-02-17

LENZ LENZ THERAPEUTICS INC4.2M sharesnew addition2025-12-312026-02-17

OLMA OLEMA PHARMACEUTICALS INC2.6M sharesnew addition2025-12-312026-02-17

Sponsored

JBIO JADE BIOSCIENCES INC3.7M sharesnew addition2025-12-312026-02-17

LBRX 2.2M sharesnew addition2025-12-312026-02-17

FDMT 5.7M sharesnew addition2025-12-312026-02-17

SYRE SPYRE THERAPEUTICS INC1.6M sharesnew addition2025-12-312026-02-17

FULC 6.6M sharesnew addition2025-12-312026-02-17

LXEO LEXEO THERAPEUTICS INC5.0M sharesnew addition2025-12-312026-02-17

MONOPAR THERAPEUTICS INC MONOPAR THERAPEUTICS INC667.2K sharesnew addition2025-12-312026-02-17

CAPR CAPRICOR THERAPEUTICS INC1.5M sharesnew addition2025-12-312026-02-17

Sponsored

ARTV ARTIVA BIOTHERAPEUTICS INC9.9M sharesnew addition2025-12-312026-02-17

IPSC 17.9M sharesnew addition2026-01-092026-01-16

IVVD 28.9M sharesnew addition2025-12-312026-02-17

MNPR 667.6K sharesnew addition2025-12-312026-02-17

GRAL GRAIL INC428.3K sharesnew addition2025-12-312026-02-17

ASSEMBLY BIOSCIENCES INC ASSEMBLY BIOSCIENCES INC1.0M sharesnew addition2025-12-312026-02-17

AVTX 1.9M sharesnew addition2025-12-312026-02-17

ABOS ACUMEN PHARMACEUTICALS INC14.9M sharesnew addition2025-12-312026-02-17

Sponsored

ALXO 13.1M sharesnew addition2026-02-022026-02-09

PALI 15.7M sharesnew addition2025-12-312026-02-17

CTNM 2.2M sharesnew addition2025-12-312026-02-17

BENITEC BIOPHARMA INC BENITEC BIOPHARMA INC1.9M sharesnew addition2025-12-312026-02-17

SRZN 871.7K sharesnew addition2025-12-312026-02-17

RZLT REZOLUTE INC9.2M sharesnew addition2025-12-312026-02-17

SAB BIOTHERAPEUTICS INC SAB BIOTHERAPEUTICS INC5.2M shares17.38%2026-03-092026-03-11

ACRV ACRIVON THERAPEUTICS INC8.3M sharesnew addition2025-12-312026-02-17

Sponsored

NKTX NKARTA INC10.8M sharesnew addition2025-12-312026-02-17

OVID OVID THERAPEUTICS INC10.7M sharesnew addition2025-12-312026-02-17

UNCY 2.4M sharesnew addition2025-12-312026-02-17

PALISADE BIO INC PALISADE BIO INC7.1M sharesnew addition2025-12-312026-02-17

CCCC C4 THERAPEUTICS INC8.0M sharesnew addition2025-12-312026-02-17

MEDLINE INC-CL A MEDLINE INC-CL A335.0K sharesnew addition2025-12-312026-02-17

DSGN DESIGN THERAPEUTICS INC1.5M sharesnew addition2025-12-312026-02-17

INSP INSPIRE MEDICAL SYSTEMS INC142.0K sharesnew addition2025-12-312026-02-17

Sponsored

AVALO THERAPEUTICS INC AVALO THERAPEUTICS INC663.0K sharesnew addition2025-12-312026-02-17

RANI RANI THERAPEUTICS HOLDINGS-A8.5M sharesnew addition2025-12-312026-02-17

PCSC PERCEPTIVE CAPITAL SOLUTIONS750.0K sharesnew addition2025-12-312026-02-17

ADICET BIO INC ADICET BIO INC948.2K sharesnew addition2025-12-312026-02-17

NAMSW NEWAMSTERDAM PHARMA CO NV-27333.3K sharesnew addition2025-12-312026-02-17

WGS GENEDX HOLDINGS CORP58.0K sharesnew addition2025-12-312026-02-17

ACET 960.2K sharesnew addition2025-12-312026-02-17

WAY WAYSTAR HOLDING CORP144.4K sharesnew addition2025-12-312026-02-17

Sponsored

HOWL WEREWOLF THERAPEUTICS INC6.7M sharesnew addition2025-12-312026-02-17

HNGE HINGE HEALTH INC-A80.1K sharesnew addition2025-12-312026-02-17

PGNY PROGYNY INC96.6K sharesnew addition2025-12-312026-02-17

QIAGEN N.V. QIAGEN N.V.44.0K sharesnew addition2025-12-312026-02-17

KIDS ORTHOPEDIATRICS CORP110.0K sharesnew addition2025-12-312026-02-17

HCAT HEALTH CATALYST INC793.7K sharesnew addition2025-12-312026-02-17

PALATIN TECHNOLOGIES INC PALATIN TECHNOLOGIES INC70.0K sharesnew addition2025-12-312026-02-17

CIDARA THERAPEUTICS INC CIDARA THERAPEUTICS INCN/A sharesSold all2026-01-072026-01-09

Sponsored

ELDN N/A sharesnew addition2025-12-312026-02-17

LRMR N/A sharesnew addition2025-12-312026-02-17

ASND

ASCENDIS PHARMA A/S - ADR

New

Shares10.3M

Event2025-12-31

Filed2026-02-17

RNA

AVIDITY BIOSCIENCES INC

New

Shares8.6M

Event2025-12-31

Filed2026-02-17

RYTM

New

Shares6.7M

Event2025-12-31

Filed2026-02-17

PCVX

VAXCYTE INC

New

Shares10.7M

Event2025-12-31

Filed2026-02-17

TYRA

TYRA BIOSCIENCES INC

0.56%

Shares12.3M

Event2026-03-04

Filed2026-03-06

SION

SIONNA THERAPEUTICS INC

New

Shares9.9M

Event2025-12-31

Filed2026-02-17

NAMS

NEWAMSTERDAM PHARMA CO NV

New

Shares9.6M

Event2025-12-31

Filed2026-02-17

WVE

WAVE LIFE SCIENCES LTD

New

Shares18.2M

Event2025-12-31

Filed2026-02-17

MLYS

MINERALYS THERAPEUTICS INC

New

Shares7.3M

Event2025-12-31

Filed2026-02-17

EWTX

EDGEWISE THERAPEUTICS INC

New

Shares10.4M

Event2025-12-31

Filed2026-02-17

DNTH

New

Shares2.6M

Event2025-12-31

Filed2026-02-17

ACET

74.09%

Shares22.6M

Event2026-04-27

Filed2026-04-29

SEPN

SEPTERNA INC

New

Shares7.0M

Event2025-12-31

Filed2026-02-17

NUVL

NUVALENT INC-A

New

Shares1.9M

Event2025-12-31

Filed2026-02-17

IRON

DISC MEDICINE INC

-11.34%

Shares2.0M

Event2025-12-31

Filed2026-02-17

JANX

JANUX THERAPEUTICS INC

New

Shares11.2M

Event2025-12-31

Filed2026-02-17

ACLX

New

Shares1.3M

Event2025-12-31

Filed2026-02-17

PEPG

PEPGEN INC

New

Shares20.1M

Event2025-12-31

Filed2026-02-17

TSHA

TAYSHA GENE THERAPIES INC

New

Shares23.6M

Event2025-12-31

Filed2026-02-17

SPRY

ARS PHARMACEUTICALS INC

New

Shares10.9M

Event2025-12-31

Filed2026-02-17

BCRX

BIOCRYST PHARMACEUTICALS INC

New

Shares15.8M

Event2025-12-31

Filed2026-02-17

BCAX

BICARA THERAPEUTICS INC

4.65%

Shares7.3M

Event2026-02-26

Filed2026-03-02

PRAXIS PRECISION MEDICINES I

New

Shares373.8K

Event2025-12-31

Filed2026-02-17

GHRS

GH RESEARCH PLC

New

Shares7.7M

Event2025-12-31

Filed2026-02-17

GERN

GERON CORP

New

Shares63.8M

Event2025-12-31

Filed2026-02-17

EVOMMUNE INC

1.04%

Shares3.5M

Event2026-02-12

Filed2026-02-17

CLYM

CLIMB BIO INC

New

Shares11.3M

Event2025-12-31

Filed2026-02-17

SOLID BIOSCIENCES INC

66.29%

Shares9.7M

Event2026-03-06

Filed2026-03-10

VOR

VOR BIOPHARMA INC

New

Shares5.4M

Event2025-12-31

Filed2026-02-17

BLTE

BELITE BIO INC - ADR

New

Shares432.5K

Event2025-12-31

Filed2026-02-17

LENZ

LENZ THERAPEUTICS INC

New

Shares4.2M

Event2025-12-31

Filed2026-02-17

OLMA

OLEMA PHARMACEUTICALS INC

New

Shares2.6M

Event2025-12-31

Filed2026-02-17

JBIO

JADE BIOSCIENCES INC

New

Shares3.7M

Event2025-12-31

Filed2026-02-17

LBRX

New

Shares2.2M

Event2025-12-31

Filed2026-02-17

FDMT

New

Shares5.7M

Event2025-12-31

Filed2026-02-17

SYRE

SPYRE THERAPEUTICS INC

New

Shares1.6M

Event2025-12-31

Filed2026-02-17

FULC

New

Shares6.6M

Event2025-12-31

Filed2026-02-17

LXEO

LEXEO THERAPEUTICS INC

New

Shares5.0M

Event2025-12-31

Filed2026-02-17

MONOPAR THERAPEUTICS INC

New

Shares667.2K

Event2025-12-31

Filed2026-02-17

CAPR

CAPRICOR THERAPEUTICS INC

New

Shares1.5M

Event2025-12-31

Filed2026-02-17

ARTV

ARTIVA BIOTHERAPEUTICS INC

New

Shares9.9M

Event2025-12-31

Filed2026-02-17

IPSC

New

Shares17.9M

Event2026-01-09

Filed2026-01-16

IVVD

New

Shares28.9M

Event2025-12-31

Filed2026-02-17

MNPR

New

Shares667.6K

Event2025-12-31

Filed2026-02-17

GRAL

GRAIL INC

New

Shares428.3K

Event2025-12-31

Filed2026-02-17

ASSEMBLY BIOSCIENCES INC

New

Shares1.0M

Event2025-12-31

Filed2026-02-17

AVTX

New

Shares1.9M

Event2025-12-31

Filed2026-02-17

ABOS

ACUMEN PHARMACEUTICALS INC

New

Shares14.9M

Event2025-12-31

Filed2026-02-17

ALXO

New

Shares13.1M

Event2026-02-02

Filed2026-02-09

PALI

New

Shares15.7M

Event2025-12-31

Filed2026-02-17

CTNM

New

Shares2.2M

Event2025-12-31

Filed2026-02-17

BENITEC BIOPHARMA INC

New

Shares1.9M

Event2025-12-31

Filed2026-02-17

SRZN

New

Shares871.7K

Event2025-12-31

Filed2026-02-17

RZLT

REZOLUTE INC

New

Shares9.2M

Event2025-12-31

Filed2026-02-17

SAB BIOTHERAPEUTICS INC

17.38%

Shares5.2M

Event2026-03-09

Filed2026-03-11

ACRV

ACRIVON THERAPEUTICS INC

New

Shares8.3M

Event2025-12-31

Filed2026-02-17

NKTX

NKARTA INC

New

Shares10.8M

Event2025-12-31

Filed2026-02-17

OVID

OVID THERAPEUTICS INC

New

Shares10.7M

Event2025-12-31

Filed2026-02-17

UNCY

New

Shares2.4M

Event2025-12-31

Filed2026-02-17

PALISADE BIO INC

New

Shares7.1M

Event2025-12-31

Filed2026-02-17

CCCC

C4 THERAPEUTICS INC

New

Shares8.0M

Event2025-12-31

Filed2026-02-17

MEDLINE INC-CL A

New

Shares335.0K

Event2025-12-31

Filed2026-02-17

DSGN

DESIGN THERAPEUTICS INC

New

Shares1.5M

Event2025-12-31

Filed2026-02-17

INSP

INSPIRE MEDICAL SYSTEMS INC

New

Shares142.0K

Event2025-12-31

Filed2026-02-17

AVALO THERAPEUTICS INC

New

Shares663.0K

Event2025-12-31

Filed2026-02-17

RANI

RANI THERAPEUTICS HOLDINGS-A

New

Shares8.5M

Event2025-12-31

Filed2026-02-17

PCSC

PERCEPTIVE CAPITAL SOLUTIONS

New

Shares750.0K

Event2025-12-31

Filed2026-02-17

ADICET BIO INC

New

Shares948.2K

Event2025-12-31

Filed2026-02-17

NAMSW

NEWAMSTERDAM PHARMA CO NV-27

New

Shares333.3K

Event2025-12-31

Filed2026-02-17

WGS

GENEDX HOLDINGS CORP

New

Shares58.0K

Event2025-12-31

Filed2026-02-17

ACET

New

Shares960.2K

Event2025-12-31

Filed2026-02-17

WAY

WAYSTAR HOLDING CORP

New

Shares144.4K

Event2025-12-31

Filed2026-02-17

HOWL

WEREWOLF THERAPEUTICS INC

New

Shares6.7M

Event2025-12-31

Filed2026-02-17

HNGE

HINGE HEALTH INC-A

New

Shares80.1K

Event2025-12-31

Filed2026-02-17

PGNY

PROGYNY INC

New

Shares96.6K

Event2025-12-31

Filed2026-02-17

QIAGEN N.V.

New

Shares44.0K

Event2025-12-31

Filed2026-02-17

KIDS

ORTHOPEDIATRICS CORP

New

Shares110.0K

Event2025-12-31

Filed2026-02-17

HCAT

HEALTH CATALYST INC

New

Shares793.7K

Event2025-12-31

Filed2026-02-17

PALATIN TECHNOLOGIES INC

New

Shares70.0K

Event2025-12-31

Filed2026-02-17

CIDARA THERAPEUTICS INC

Sold all

SharesN/A

Event2026-01-07

Filed2026-01-09

ELDN

New

SharesN/A

Event2025-12-31

Filed2026-02-17

LRMR

New

SharesN/A

Event2025-12-31

Filed2026-02-17

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available